co-localization analysis of proteins based on confocal laser or optical
It is an essential tool for modern confocal microscopy and will facilitate
researcher understanding of the dynamic interaction between proteins.
MICA is a high-throughput software, based on newly developed algorithms
that can facilitate development of novel diagnostic, prognostic and therapy
MICA supports simultaneous analysis of many images (2D and 3D) grouped
according to dose or time. It uses proprietary algorithms to characterize
and then quantify the co-localization between proteins and perform the
analysis, evenly, on all groups and images. The statistical variability
and significance of measurements between the groups is then assessed in
a variety of analysis methods. Paper-ready output containing textual reports
and colorful image galleries can then be created.
MICA has some unique advantages over other tools in
• High throughput - the ability to conduct large scale experiment
• Measuring and comparing images in an accurate and objective manner
• Sophisticated analysis, using state of the art proprietary algorithms
• Extensive output capabilities, both textual and graphical
To download a copy of MICA’s white paper click
Image Gallery: A screen shot from MICA, showing the image groups on
the left and the respective gallery on the right.